The testosterone in the Androderm® 2 mg/day and 4 mg/day patches is contained within the center of the patch and surrounded by an adhesive that you stick onto your skin. Because there is a low risk of spreading testosterone, when you’re wearing the Androderm® patch, you can shake hands with a coworker, hug your partner, or give your child or grandchild that piggyback ride.

Wait 3 hours before showering, bathing, or swimming after applying Androderm®. Androderm® does not need to be removed during sex or while you take a shower or bath.

Strenuous exercise or excessive perspiration may loosen the patch or cause it to fall off. IMPORTANT RISK INFORMATION Who should not use ANDRODERM? Do not use ANDRODERM if you: • are a man who has breast cancer • have or might have prostate cancer • are pregnant or may become pregnant or are breastfeeding.

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ANDRODERM may harm your unborn or breastfeeding baby INDICATION ANDRODERM is a prescription medicine that contains testosterone. ANDRODERM is used to treat adult males who have low or no testosterone due to certain medical conditions. Your healthcare provider will test your blood for testosterone before you start and while you are taking ANDRODERM. It is not known if ANDRODERM is safe and effective to treat men who have low testosterone due to aging.

It is not known if ANDRODERM is safe and effective in children younger than 18 years old. Improper use of ANDRODERM may affect bone growth in children. ANDRODERM is a controlled substance (CIII) because it contains testosterone that can be a target for people who abuse prescription medicines. Keep your ANDRODERM in a safe place to protect it. Never give your ANDRODERM to anyone else, even if they have the same symptoms you have. Selling or giving away this medicine may harm others and it is against the law. ANDRODERM is not meant for use by women.

IMPORTANT RISK INFORMATION (cont’d) What should I tell my healthcare provider before using ANDRODERM? Before you use ANDRODERM, tell your healthcare provider if you: • have breast cancer • have or might have prostate cancer • have urinary problems due to an enlarged prostate • have heart problems • have kidney or liver problems • have problems breathing while you sleep (sleep apnea) • have diabetes • have any other medical conditions Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Using ANDRODERM with other medicines can affect how ANDRODERM works and how other medicines work. Especially, tell your healthcare provider if you take: • insulin • medicines that decrease blood clotting • corticosteroids What are the possible side effects of ANDRODERM? ANDRODERM can cause serious side effects including: • If you already have an enlargement of your prostate gland your signs and symptoms may get worse while using ANDRODERM.

Beta Blockers. How Does the Nitroglycerin Patch Work? This medicine does not start working fast enough to actually treat an angina attack that has.

This can include: • increased urination at night • trouble starting your urine stream • having to pass urine many times during the day • having an urge that you have to go to the bathroom right away • having a urine accident • being unable to pass urine or weak urine flow • Possible increased risk of prostate cancer. Your healthcare provider should check you for prostate cancer or any other prostate problems before you start and while you use ANDRODERM. • Blood clots in the legs or lungs. Signs and symptoms can include leg pain, swelling or redness of your legs, difficulty breathing or chest pain.

• Possible increased risk of heart attack or stroke. • In large doses ANDRODERM may lower your sperm count. • Swelling of your ankles, feet, or body, with or without heart failure. • Enlarged or painful breasts. • Problems breathing while you sleep (sleep apnea). Call your healthcare provider right away if you have any of the serious side effects listed above.